Expression of Testis Specific Genes TSGA10, TEX101 and ODF3 in Breast Cancer

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Expression of Testis Specific Genes TSGA10, TEX101 and ODF3 in Breast Cancer

BACKGROUND Breast cancer is the most common malignancy in women around the world so finding new biomarkers for early detection and also study on molecular aspects of breast cancer is valuable. Cancer testis genes are a group of genes expressed solely in testis and in a range of human malignancies. OBJECTIVES In this study we determined the expression of cancer testis genes Tsga10, TEX101 and ...

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expression of testis specific genes tsga10, tex101 and odf3 in breast cancer

background breast cancer is the most common malignancy in women around the world so finding new biomarkers for early detection and also study on molecular aspects of breast cancer is valuable. cancer testis genes are a group of genes expressed solely in testis and in a range of human malignancies. objectives in this study we determined the expression of cancer testis genes tsga10, tex101 and od...

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Investigating specific expression of ADAM29, FTHL17, and HORMAD1 cancer/testis genes in glioblastoma tumors

Introduction: Glioblastoma primary brain tumor.Immunotherapy is a promising therapeutic adjuvant in fighting against this cancer.  Cancer/testis antigens (CTAs) are a group of tumor-associated antigens that are typically restricted to adult testis, but they are aberrantly expressed in several types of cancers, especially in advanced cancers with stem-like characteristics. These tumor-associate...

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piwil2 and pl2l60 (cancer/testis genes) expression in breast cancer

background: cancer/testis antigens (ctas) are members of a group of proteins which are normally expressed in testis germ cells and to a lesser extent in the ovaries. because of recent reports about their aberrant and specific expression in some tumoral tissues, they may play a role as new candidates for targeted therapy. therefore, the study of the expression pattern of these biomarkers and its...

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Expression of splice variants of cancer-testis genes ODF3 and ODF4 in the testis of a prostate cancer patient.

The outer dense fiber (ODF) genes encode proteins that co-assemble along the axoneme of the sperm tail. Recently, it was demonstrated that some ODF genes are aberrantly expressed in tumors, including prostate adenocarcinoma, basal cell carcinoma, and chronic myeloid lymphoma. We cloned ODF3 and ODF4 cDNA from the testis of a patient suffering from prostate adenocarcinoma and found two alte...

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ژورنال

عنوان ژورنال: Iranian Red Crescent Medical Journal

سال: 2012

ISSN: 2074-1804,2074-1812

DOI: 10.5812/ircmj.3611